Determining whether LV filling time contributes to HF symptoms in different widths of QRS in LBBB patients: A clinical study.

OBJECTIVES: Accurate assessment of left ventricular (LV) function is essential for managing patients with left bundle branch block (LBBB). This study aimed to evaluate the relationship between LV systolic function, left ventricular diastolic filling time (LVFT), QRS duration, and heart failure symptoms in patients with LBBB. METHODS: This study was conducted between June 2021 and June 2022. Patients with LBBB and sinus rhythm who were referred to the echocardiography department were included in the study. All the patients underwent electrocardiogram-gated echocardiography using the same machine. In this study, the LVFT value was measured in absolute terms and as a ratio to the R-R interval (LVFT/RR). RESULTS: A total of sixty-five patients were included, forty-two (64.6%) were women, and the mean age was 60.71 ± 8.72. We performed three one-way ANOVA tests that showed that LV filling time/RR ratio, QRS duration, and ejection fraction were significantly different between heart failure classes (p = 0.008, p = 0.001, and p < 0.001, respectively). A weak correlation was observed between LVEF and LVFT/RR (r = 0.349, p = 0.004). Additionally, QRS duration was negatively correlated with LVEF (r =  - 0.395, p = 0.004) and LVFT/RR (r =  - 0.350, p = 0.004), although these correlations were weak. CONCLUSION: We showed that LVFT/RR ratio differed significantly between HF functional classes and was lower in patients with more severe HF symptoms. Additionally, QRS duration was negatively correlated with LVEF and LVFT/RR, and patients with more severe HF symptoms had longer QRS durations.

Conventional and two-dimensional strain echocardiography in predicting postoperative atrial fibrillation after coronary artery bypass grafting surgery.

Background: Atrial fibrillation (AF) is a common complication after heart surgeries. Advances in imaging technologies and an understanding of the pathophysiology of preoperative left atrial (LA) dysfunction can lead to more definitive potential therapeutic approaches. This study aimed to determine the role of conventional echocardiography and LA two-dimensional (2D) strain echocardiography in assessing LA function and predicting POAF after CABG surgery. Methods: All patients with sinus rhythm who underwent CABG surgery were enrolled. All the patients had undergone conventional echocardiography and LA 2D-strain echocardiography 24 hours before surgery. In addition to demographic, clinical, and perioperative features, electrocardiogram (ECG) and Holter monitoring were recorded. Results: Of the 105 patients included, 85 patients (81%) were men with a mean age of 60.26±10.61 years. POAF was seen in 22.9% of patients during hospitalization, and AF duration was 10 hours (median; IQR: 2.0-19.5). AF patients had a higher LA volume index (LAVI) than patients with sinus rhythm (p=0.018). Patients with sinus rhythm had higher rates of LA reservoir (26.97±6.87 VS. 20.46±4.27, p<0.001), LA contractile (14.98±3.68 VS. 12.76±3.72, p =0.012) and LA global strain (24.28±6.57 VS. 17.71±4.11, p<0.001) than AF patients. The results of the multivariate logistic regression showed that LAVI (p=0.014) and LA global strain (p=0.027) were independent predictors of AF detection. Conclusion: Compared to conventional echocardiography, 2D-strain echocardiography is a more effective diagnostic method to predict the possibility of post-CABG AF.

Left ventricle assessment by three-dimensional HeartModel software in different types of mitral valve prolapse (Barlow's disease and fibroelastic deficiency) with severe mitral regurgitation.

BACKGROUND: Mitral valve prolapse (MVP) is the most common cause of isolated mitral regurgitation (MR) requiring surgical repair. Therapeutic interventions should be considered before irreversible left ventricular (LV) dysfunction in asymptomatic patients. Measurement of LV volume and function is very important. Because of two-dimensional (2D) echocardiography limitations, three-dimensional (3D) measurement is preferred on the strength of its speed, accuracy, and reproducibility, which are comparable with those of magnetic resonance imaging (MRI). METHODS: This study was conducted between April 2018 and February 2019 on 50 patients with different MVP types and severe MR scheduled for valve surgery at Rajaie Cardiovascular Research Center, Tehran, Iran, with the aid of the HeartModelAnatomical intelligence (A.I.) (EPIQ 7: new 3D software) for measurement of LV volume indices and function. RESULTS: Patients with the Barlow syndrome had a greater drop in LV ejection fraction (LVEF) than those with fibroelastic deficiency (FED) (57.05% ± 6.00% vs. 65.00% ± 4.08%; P = 0.001). LV volume was larger in patients with flail mitral valve (MV) than in those with non-flail MV (165 cc vs. 118 cc; P = 0.001). LVEF declined more in patients with the involvement of both leaflets than in those with the involvement of the anterior leaflet alone (56.00% ± 7.10% vs. 57.70% ± 4.30%; P = 0.021). CONCLUSION: The LVEF drop was more remarkable in patients with the Barlow syndrome (both flail and non-flail MV) than in those with FED. It is, therefore, advisable that such patients be monitored more meticulously via the 3D HeartModelA.I. method in terms of LVEF and LV size to prevent irreversible effects on LV function and to reduce mortality.

Congenital Morgagni hernia in a middle-aged woman presenting with chest pain. / Hernia congénita de Morgagni en una mujer de mediana edad que presenta dolor torácico

A 56-year-old woman with a history of type II diabetes, hypertension, and hyperlipidemia presented to the emergency department with retrosternal chest pain that had increased over the past 5 days. She was experiencing a localized chest pressure that was aggravated with eating and physical activity. The medical history was negative for coronary artery disease or any other cardiac diseases.

Outcome of surgical embolectomy in patients with massive pulmonary embolism with and without cardiopulmonary resuscitation.

INTRODUCTION: Pulmonary embolism is a challenging critical cardiovascular disease with high morbidity and mortality. Surgical embolectomy has favorable results in patients with massive pulmonary embolism. AIM: To study the outcome of embolectomy in patients with massive pulmonary embolism. MATERIAL AND METHODS: In this single-center, retrospective study, 36 patients including 14 male and 22 female patients with a mean age of 50.80 ±18.89 years with acute pulmonary embolism who underwent surgical pulmonary embolectomy from January 2011 to January 2016 were included. The medical records of all patients were reviewed for demographic and preoperative data and postoperative outcomes. RESULTS: Common risk factors for acute PE were major surgery within 3 months and deep vein thrombosis. The most common presenting symptoms of patients were dyspnea, followed by chest pain and syncope. Mean duration of hospitalization was 14.76 ±8.69 days and mean operation duration was 4.47 ±1.54 h. Mean time from admission to embolectomy was 6.58 ±1.13 h. Ten (27.8%) patients died during the operation including 3 cases with cardiopulmonary resuscitation prior to surgery and 2 cases with severe cardiogenic shock. Patients who survived were followed for 6 months. The mortality rate during follow-up was 15.4%; all 4 patients died during follow-up period due to metastatic cancer. No pulmonary embolism recurrance were seen. CONCLUSIONS: Although surgical embolectomy mostly was done for high risk patients, it had good in-hospital and excellent mid-term outcomes.